Community Forum Archive

The Epilepsy Community Forums are closed, and the information is archived. The content in this section may not be current or apply to all situations. In addition, forum questions and responses include information and content that has been generated by epilepsy community members. This content is not moderated. The information on these pages should not be substituted for medical advice from a healthcare provider. Experiences with epilepsy can vary greatly on an individual basis. Please contact your doctor or medical team if you have any questions about your situation. For more information, learn about epilepsy or visit our resources section.

Keppra - positive/negative experiences?

Fri, 04/06/2018 - 12:15
I would just like to find out generally what people's experiences are with Keppra (Levetiracem)? I am currently taking 125mg x 2 per day Lamotrigine, in the process of increasing my dose due to recent seizures, but the medication still doesn't seem to be working as I had another tonic-clonic yesterday. As an alternative my neurologist has recommended Keppra but it is ultimately up to me to decide whether I should continue to try increasing my Lamictal (which is the only AED I've ever taken since I was diagnosed 7 years ago), or to switch to Keppra. I have only ever heard bad things about Keppra side effects (depression, anger, etc) so am very wary of switching. What have people's experiences of Keppra been?

Comments

As an alternative my

Submitted by just_joe on Fri, 2018-04-06 - 15:59
As an alternative my neurologist has recommended Keppra but it is ultimately up to me to <<< Your doctor is letting you know that keppra may be the medication that will control your seizures better. He is leaving the decision up to you.You seem to b concerned about the side effects since almost all the reviews I have seem are written by people that got one. Please understand that side effects do happen. But with most there at generally 5-8% of the people taking that medications that get them. Meaning 92-95% of the people taking it have had no side effects or they went away after their body got used to the medication. I have been taking keppra for over 15 years and have never had a problem with it

not every drug is limited to

Submitted by Amy Jo on Sun, 2018-04-08 - 10:32
not every drug is limited to only 8% of people experiencing a side effect, compare (cut & paste as there’s no automatic recognition of what’s a link in the editor) your experience with lamotrigine https://reference.medscape.com/drug/lamictal-lamotrigine-343012#4check out common side effects of keppra https://reference.medscape.com/drug/keppra-spritam-levetiracetam-343013#4

I switched from depakote

Submitted by EPinDC on Sat, 2018-04-14 - 08:12
I switched from depakote (valproate) to keppra (levetiracetam) about a year ago. For me, the experience has been mixed. Fyi: I'd been on depakote (1000 mg/day) for over 25 years and had not had a lot of problematic side effects until the last 3 years when I started having a host of issues. The keppra (750 mg/day) has been rough for me although I feel that it controls the seizures well. The major side effects that I've experienced have been the usual ones that you've no doubt heard: anxiety, sleeplessness, anger, moodiness, exhaustion, lack of motivation, and depression. I've also developed some fairly serious stomach problems but I'm not sure if that's related or not. I should emphasize that I've had all of these symptoms-to some degree-before the keppra but I feel that it's exacerbated many of them. Additionally, my previous medication may have masked certain other characteristics.The only exception to this would be the moodiness which has never been a problem for me before. If you are taking a lower does (500 mg total or less), however, the negative impact may be significantly less. A lot of the stories about keppra are extremely negative but I've also seen a some really positive comments; as many have commented, much of this depends on your individual chemistry and preferences. I wish you all the best.

Sign Up for Emails

Stay up to date with the latest epilepsy news, stories from the community, and more.